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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRC1 All Species: 18.48
Human Site: S610 Identified Species: 40.67
UniProt: O43663 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43663 NP_003972.1 620 71607 S610 A S K S D A T S G I L N S T N
Chimpanzee Pan troglodytes XP_510600 770 87232 S760 A S K S D A T S G I L N S T N
Rhesus Macaque Macaca mulatta XP_001098763 640 74381 N610 A C N G R Q F N S I E G D V C
Dog Lupus familis XP_849989 620 71878 S610 A S K S D A T S R I L N S T N
Cat Felis silvestris
Mouse Mus musculus Q99K43 603 70244 S593 A S R S D A T S R I L N S T N
Rat Rattus norvegicus NP_001100999 606 70580 S596 A S R S D A T S R I L N S T N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001073221 262 30135 N253 W E R L Q V P N E E R E A F A
Frog Xenopus laevis NP_001080868 609 71186 P597 A T R S N T N P H I L N S T I
Zebra Danio Brachydanio rerio NP_956528 605 70353 P595 S S K S K H V P E I L N S T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572659 607 71048 S598 P S G E E N E S P D E E A V V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785901 748 86941 V733 N N M S T L S V T S S Y Q R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.3 89.8 93 N.A. 81.2 81.2 N.A. N.A. 28.5 61.9 59 N.A. 22.2 N.A. N.A. 31.2
Protein Similarity: 100 78.4 92.5 95.8 N.A. 88.3 88.8 N.A. N.A. 35.6 76.2 73.3 N.A. 43.5 N.A. N.A. 48.1
P-Site Identity: 100 100 13.3 93.3 N.A. 86.6 86.6 N.A. N.A. 0 46.6 53.3 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 100 20 93.3 N.A. 93.3 93.3 N.A. N.A. 20 66.6 60 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 64 0 0 0 0 46 0 0 0 0 0 0 19 0 10 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 46 0 0 0 0 10 0 0 10 0 0 % D
% Glu: 0 10 0 10 10 0 10 0 19 10 19 19 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 10 10 0 0 0 0 19 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 73 0 0 0 0 19 % I
% Lys: 0 0 37 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 0 10 0 0 0 0 64 0 0 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 10 0 10 10 10 19 0 0 0 64 0 0 46 % N
% Pro: 10 0 0 0 0 0 10 19 10 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 10 10 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 37 0 10 0 0 0 28 0 10 0 0 10 0 % R
% Ser: 10 64 0 73 0 0 10 55 10 10 10 0 64 0 0 % S
% Thr: 0 10 0 0 10 10 46 0 10 0 0 0 0 64 0 % T
% Val: 0 0 0 0 0 10 10 10 0 0 0 0 0 19 10 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _